Marco A.N. Domingos

This paper develops bio-fabricated alginate hydrogels to model prostate cancer microenvironments, showing increased cell proliferation and metastatic markers in stiffer, laminin-enriched hydrogels with cancer-associated fibroblasts.

This paper introduces a topography-driven platform for stem cell differentiation without biochemical cues, showing it induces osteogenesis through mechanotransduction and Hedgehog signaling.

This study optimizes self-assembling peptide hydrogels to better support mammary epithelial cell organoid formation compared to Matrigel.

This study shows that adding TTNPB and timed BMP2 to hPSC differentiation improves chondrogenesis, upregulating genes related to skeletal and cartilage development.