Author
Centre National de la Recherche ScientifiqueORCID 0000-0002-6704-2032Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Margaux Oberling, Mathieu Landry, Yann Aubert…·Margherita Ghisi
This study identifies PTBP1-CDC42 splicing regulation as a critical factor in AML growth and venetoclax sensitivity, suggesting a therapeutic combination strategy.
Binje Vick, Vindi Jurinović, Kristina Kuhbandner…·Irmela Jeremias
The paper develops patient-derived AML PDX models that replicate primary AML biology and include subgroups lacking existing models, showing reduced leukemia growth after long-term chemotherapy.
Sarah J. Skuli, A’ishah Bakayoko, Marisa Kruidenier…·Martin P Carroll
This study identifies GGPP, a mevalonate pathway byproduct, as critical for chemoresistance in TP53mut AML through ROS regulation and mitochondria stress response, suggesting statin-based therapies could be effective.
Clément Larrue, Sarah Mouche, Paolo Angelino…·Jérôme Tamburini
The paper identifies ferritinophagy as a therapeutic target in quiescent leukemic stem cells, showing that inhibiting NCOA4 reduces leukemia.
Vilma Dembitz, Hannah Lawson, Richard Burt…·Paolo Gallipoli
SCD inhibition induces AML cell death and synergizes with chemotherapy to prolong survival in murine AML models.