Ann Regina Falsey

The paper integrates multi-omic data to identify cellular pathways associated with RSV severity in infants.

The paper develops a gene expression risk score to predict severe COVID-19 illness using peripheral blood samples and validates it in independent cohorts.

The paper identifies a lack of airway interferon activation as a marker of severe infant RSV infection and shows that blocking IFN signaling increases viral infection in vitro.

The paper introduces efficient hypothesis testing methods for regression-type tests with correlated data and heterogeneous variance, outperforming existing methods in speed and accuracy.

The paper examines co-occurrence patterns of gut and respiratory microbiota in pre- and full-term infants over the first year, identifying three patterns of CST manifestation related to infant maturity.