Valerian E. Kagan

The paper shows that hydroperoxy-phospholipids are necessary but insufficient for ferroptosis, requiring additional Fe-catalyzed processes and agents to complete the death program.

This study shows targeting the LxCxE cleft pocket of Rb in M2 macrophages inhibits ovarian cancer progression by reducing immunosuppressive TAMs and enhancing T cell infiltration.

This study identifies conjugated linolenic acids as ferroptosis inducers in triple-negative breast cancer and shows their anti-tumor effects in a xenograft model.