GenomicsScientific ReportsPeer-reviewed
Systematic dissection of biases in whole-exome and whole-genome sequencing reveals major determinants of coding sequence coverage
Yury A. Barbitoff, Dmitrii E. Polev, Andrey Sergeyevich Glotov…·Alexander V. Predeus
This study systematically evaluates coverage biases in whole-exome and whole-genome sequencing, finding that some WES platforms outperform others and that WES can match WGS in variant discovery.
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