Erik P. Storrs

The paper creates a spatial atlas of early-stage colorectal cancer tumors to identify bacterial niches and their impact on tumor transcriptomes, highlighting C. difficile's significant influence despite low abundance.

MOSAICField aligns spatial slices across modalities to reconstruct 3D tissue models and map morphology, outperforming existing methods on simulated and prostate cancer data.

This study identifies breast cancer subtypes and their lineage origins by analyzing chromatin accessibility and transcriptional dynamics using multi-omic techniques.