Laura Richardson

This paper creates a detailed heart atlas using multimodal data to identify cell states and disease-associated genetic variants in specific heart regions.

The paper profiles immune cell RNA and protein expression across tissues and age to identify tissue-specific and age-related immune signatures.

This study constructs a multiomic atlas of human early skeletal development using single-nuclei transcriptomics, epigenomics, and spatial transcriptomics to uncover regulatory mechanisms and cell states involved in bone and joint formation.

This study develops a multi-omic reference of human cardiac development and identifies disruptions in Trisomy 21 hearts.

This paper uses spatial transcriptomics and single-cell data to identify cellular niches in the human heart, revealing new insights into cardiac function and potential drug targets.

The paper constructs a human fetal lung cell atlas from 5-22 post conception weeks, identifying new cell states and regulators of epithelial fates.

The paper presents a pan-cancer proteomic map of 949 cell lines, revealing protein-specific biomarkers of cancer vulnerabilities and showing proteomic data's superior predictive power for drug response.

This study integrates drug sensitivity data with CRISPR screens to identify drug mechanisms and biomarkers for cancer therapy.