NeurosciencebioRxivPreprint
Sofosbuvir protects human brain organoids against SARS-CoV-2
Pinar Mesci, Ángela Macia, Aurian Saleh…·Alysson Renato Muotri
SARS-CoV-2 infects and kills neural cells in iPSC-derived human brain organoids and impairs synaptogenesis; the approved antiviral sofosbuvir is reported to reverse both effects.
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