Molecular BiologybioRxivPreprint
EZH1 Q571R-mediated chromatin compaction and its oncogenic potential in thyroid cancer
Hanbyeol Kim, Do‐Gyun Kim, Seongyun Ha…·Chul‐Hwan Lee
This study shows that the EZH1Q571R mutation enhances chromatin compaction and PRC2 activity, leading to repression of tumor suppressor genes in follicular thyroid cancer.