Author

Melin Janardan Khandekar

Harvard UniversityORCID 0000-0002-9033-3241Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aaron R. ThorneriD· 1 shared Aarti H. AsnaniiD· 1 shared Alexandra KuznetsoviD· 1 shared Amanda GarzaiD· 1 shared Amanda L. SmythersiD· 1 shared Anthony RosenzweigiD· 1 shared Anwesha NagiD· 1 shared Ariana Vargas‐CastilloiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Aaron R. ThornerORCID

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2 papers

Recent·Most cited

Cancer BiologyScience Translational MedicinePeer-reviewedJan 21, 2026

Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity

Erica Maria Pimenta, Amanda Garza, Sabrina Yvonne Camp…·Eliezer M. Van Allen

This study identifies epigenetic dysregulation of metabolic programs in liposarcoma, linking IGF1 loss and PPARG2 deficiency to dedifferentiation and proposing IGF1R-targeted therapy.

5 citationstop 1%

humanscRNA-seq

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PhysiologyNature Cardiovascular ResearchPeer-reviewedSep 24, 2025

Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy

Sumeet A. Khetarpal, Haobo Li, Tevis Vitale…·Anthony Rosenzweig

This study shows that cardiomyocyte PGC-1α is essential for cardiac adaptation to endurance exercise by suppressing GDF15 and preventing cardiac atrophy in mice.

8 citationstop 5%

mousebulk RNA-seq

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