Nianping Liu

This study compares 7 analysis pipelines and 7 experimental methods for detecting extrachromosomal circular DNA, identifying the most effective approaches for short-read and long-read sequencing data.

WEDGE imputes gene expression values in single-cell RNA-seq datasets using biased matrix decomposition, improving clustering and correlation recovery in sparse data.

This study uses single-cell RNA sequencing to analyze immune responses in COVID-19 patients, identifying key immune cell changes and molecular pathways linked to disease severity.