Molecular BiologyJournal of Medicinal ChemistryPeer-reviewed
Discovery of a first-in-class small molecule ligand for WDR91 using DNA-encoded chemical library selection followed by machine learning
Shabbir Ahmad, Jin Bao Xu, Jianwen A. Feng…·Levon Halabelian
The paper identifies a first-in-class small molecule ligand for WDR91 using DNA-encoded chemical library selection and machine learning, leading to the discovery of covalent analogs and structural insights.