BiophysicsbioRxivPreprint
Post-translational acylation drives folding and activity of the CyaA bacterial toxin.
Corentin C. Leger, Samuel Hoff, Gaia Scilironi…·Alexandre Chenal
This study shows that acylation stabilizes the native fold of CyaA and facilitates its membrane orientation, revealing how post-translational modification drives toxin activity.
DOI 10.1101/2025.09.11.673628