Author

Paul D. Barker

University of CambridgeORCID 0000-0003-0094-0054Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Anne-Cathrin Prowald· 1 shared Florian HollfelderiD· 1 shared Friederike E. H. NintzeliD· 1 shared Matthew PenneriD· 1 shared Maximilian GantziD· 1 shared Oskar James KleiniD· 1 shared Paul DupreeiD· 1 shared Sally R. BossiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Anne-Cathrin Prowald

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1 paper

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedMar 24, 2025

Fluorogenic, sub-single-turnover monitoring of enzymatic reactions involving NAD(P)H provides a generalised platform for directed ultrahigh throughput evolution of biocatalysts in microdroplets

Matthew Penner, Oskar James Klein, Maximilian Gantz…·Florian Hollfelder

The paper develops a fluorogenic assay for NAD(P)H detection to enable high-throughput screening of biocatalysts in microdroplets, demonstrating improved sensitivity and applicability for glycosyl hydrolases and IREDs.

14 citations

proteomicsdeep learning

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