Martin Jastroch

This study reveals the mechanism of UCP1-mediated proton and fatty acid transport using molecular simulations and mutagenesis, showing how proton transfer and FA movement are facilitated by specific residues and conformational changes.

This study uses single-cell RNA sequencing to identify shared mitochondrial dysfunction in motor neurons across FUS and TARDBP ALS mutations, suggesting common toxic mechanisms.

This paper identifies IF1 as a cold-regulated inhibitor of ATP synthase that facilitates reverse mode activity in brown fat to support thermogenesis.