Author

Kai Yi

UNSW SydneyORCID 0000-0003-0415-3584Unclaimed ORCID profile · follow to get notified of new preprints

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Kai Yi1 paper · MRC Laboratory of Molecular Biology

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein design· 2 Assay:protein sequence· 2 Approach:diffusion model· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein structure prediction· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

Banghao WuiD· 2 shared Bozitao ZhongiD· 2 shared Liang HongiD· 2 shared Lirong ZhengiD· 2 shared Yang TaniD· 2 shared Bingxin Zhou· 1 shared Guisheng FaniD· 1 shared Outongyi Lv· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioengineering

Banghao WuORCID

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2 papers

Recent·Most cited

BioengineeringCell DiscoveryPeer-reviewedSep 9, 2024

A conditional protein diffusion model generates artificial programmable endonuclease sequences with enhanced activity

Bingxin Zhou, Lirong Zheng, Banghao Wu…·Liang Hong

This paper introduces CPDiffusion, a conditional protein diffusion model that generates artificial endonuclease sequences with enhanced activity without labeled data.

36 citationstop 4%

protein sequencedeep learning

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BioengineeringJournal of Chemical Information and ModelingPeer-reviewedApr 17, 2024

Protein Engineering with Lightweight Graph Denoising Neural Networks

Bozitao Zhong, Lirong Zheng, Banghao Wu…·Liang Hong

This study introduces a lightweight graph neural network for protein engineering that predicts fitness and guides the design of effective mutants with improved physicochemical properties.

39 citationstop 4%

protein sequencedeep learning

𝕏 PostBluesky