Author

Jennifer O’Sullivan

Guy's HospitalORCID 0000-0003-0502-7133Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adam J. MeadiD· 2 shared Alba Rodríguez-MeiraiD· 2 shared Bethan PsailaiD· 2 shared Supat ThongjueaiD· 2 shared Alex J. CornishiD· 1 shared Amir EnshaeiiD· 1 shared Anastasios Karadimitiris· 1 shared Angela D. HambliniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Adam J. MeadORCID

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2 papers

Recent·Most cited

Cancer BiologyNature GeneticsPeer-reviewedJun 1, 2025

Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A

Charlotte K. Brierley, Bon Ham Yip, Giulia Orlando…·Adam J. Mead

The paper identifies chromothripsis-induced amplification of DYRK1A in blast phase MPN as a driver of aggressive disease and a potential therapeutic target.

14 citationstop 3%

humanbulk RNA-seq

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Developmental BiologybioRxivPreprintApr 20, 2021

Developmental stage- and site-specific transitions in lineage specification and gene regulatory networks in human hematopoietic stem and progenitor cells

Anindita Roy, Guanlin Wang, Deena Iskander…·Supat Thongjuea

This study identifies site- and stage-specific transitions in gene regulatory networks and lineage specification in human hematopoietic stem and progenitor cells across developmental stages.

DOI 10.1101/2021.04.20.440420

humanscRNA-seq

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