Skyler A. Kuhn

The paper investigates how TRIM5α restricts orthoflavivirus replication and identifies a mutation in POWV's NS3 gene that allows it to evade TRIM5α inhibition.

This study identifies over 2,000 GC-responsive non-coding transcripts across nine human cell types, revealing cell-type-specific regulation of lncRNAs and miRNAs.

The paper links adverse social determinants of health to NK cell dysfunction through obesity, LDL, and DUSP1 signaling in African-American women.

This study identifies MATRIN3 deficiency as a trigger for autoinflammation through cGAS-STING activation via mis-splicing of TDRD3 and R-loop formation.

This study demonstrates that cfChIP-seq can reliably detect gene signals and tissue sources of cfDNA in physiological and heart transplant patients, identifying pathway changes in immunosuppressed individuals.