Author

Michael S. Perkinton

AstraZeneca (United Kingdom)ORCID 0000-0003-1130-7844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew Billinton· 1 shared Emily TalbotiD· 1 shared Frederick J. LiveseyiD· 1 shared Graham Mathew FraseriD· 1 shared James C. SmithiD· 1 shared Kalliopi Tsafou· 1 shared Lewis EvansiD· 1 shared Lisha JoshiiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Andrew Billinton

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cell BiologyNucleic Acids ResearchPeer-reviewedNov 29, 2023

The cGAS-STING pathway regulates microglial chemotaxis in genome instability

Emily Talbot, Lisha Joshi, Peter Thornton…·Svetlana V. Khoronenkova

This study shows that the cGAS-STING pathway drives microglial chemotaxis and inflammation in response to DNA damage, linking genome instability to neuroinflammation.

41 citationstop 5%

humanbulk RNA-seq

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NeuroscienceCell ReportsPeer-reviewedMar 1, 2018

Extracellular monomeric and aggregated tau efficiently enter human neurons through overlapping but distinct pathways

Lewis Evans, Thomas Wassmer, Graham Mathew Fraser…·Frederick J. Livesey

The paper investigates how monomeric and aggregated tau enter human neurons through distinct pathways, identifying dynamin- and actin-dependent mechanisms for monomeric tau and dynamin-dependent clathrin-mediated endocytosis for aggregated tau.

192 citationstop 1%

humanexperimental assay

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