Author

Burak Soysal

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research InstituteORCID 0000-0003-1880-1511Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Philip N. TsichlisiD· 3 shared Alessandro La FerlitaiD· 2 shared Evangelia Chavdoula· 2 shared Giovanni NigitaiD· 2 shared Ilaria CosentiniiD· 2 shared Vollter AnastasiD· 2 shared Anika S. Yadati· 1 shared Anuvrat Sircar· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

Philip N. TsichlisORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 30, 2024

Multiplexed functional analysis of TAP2 variants in regulating MHC-I cell surface abundance reveals overexpression of PLK1 downregulates antigen presentation.

Gregory Nagy, Rebecca Presley, Hyeongseon Jeon…·Jeffrey D. Parvin

The paper functionally screens TAP2 variants to show PLK1 overexpression reduces MHC-I surface abundance by phosphorylating TAP2, impairing antigen presentation in cancer cells.

2 citations

humanproteomics

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Cancer BiologybioRxivPreprintMay 22, 2024

KDM2B is required for ribosome biogenesis and its depletion unequally affects mRNA translation

Vollter Anastas, Evangelia Chavdoula, Alessandro La Ferlita…·Philip N. Tsichlis

This study shows KDM2B promotes ribosome biogenesis by enhancing transcription of ribosome-related genes and affects mRNA translation unequally based on mRNA features.

3 citations

humanbulk RNA-seq

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Cancer BiologyMetabolismPeer-reviewedJul 8, 2023

Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

Evangelia Chavdoula, Vollter Anastas, Alessandro La Ferlita…·Philip N. Tsichlis

This study identifies KDM2B's role in regulating amino acid metabolism through interactions with ncPRC1.1, MYC, and ATF4, revealing a metabolic network linked to poor prognosis in TNBC.

20 citations

humanbulk RNA-seq

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