BiochemistryNature CommunicationsPeer-reviewed
PTPN2 copper-sensing rapidly relays copper level fluctuations into EGFR/CREB activation and associated CTR1 transcriptional repression
Matthew O. Ross, Yuan Xie, Ryan C. Owyang…·Chuan He
The paper identifies PTPN2 as a copper sensor that modulates EGFR/CREB signaling and CTR1 transcriptional repression in response to copper level changes.
18 citations