This study investigates the role of IL10 in avian mucosal immunity by generating IL10-deficient chickens, showing altered microbiome composition and enhanced pathogen clearance with increased inflammation.

6 citations

chicken / avianproteomics

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedOct 1, 2024

Spatial distribution of poultry farms using point pattern modelling: a method to address livestock environmental impacts and disease transmission risks

Marie-Cécile Dupas, Francesco Pinotti, Chaitanya G. Joshi…·Guillaume Fournié

This paper develops a farm distribution model to predict poultry farm locations and sizes in data-scarce regions, showing that spatial clustering increases disease transmission risk.

4 citations

statistical modelbenchmarking

𝕏 PostBluesky

MicrobiologymSystemsPeer-reviewedSep 17, 2024

Multi-omics analysis reveals regime shifts in the gastrointestinal ecosystem in chickens following anticoccidial vaccination and Eimeria tenella challenge

Po‐Yu Liu, Janie Liaw, Francesca Soutter…·Dong Xia

This study uses multi-omics analysis to identify shifts in the chicken gastrointestinal ecosystem following vaccination and Eimeria tenella challenge, revealing distinct metabolic and microbial profiles associated with health, infection, and recovery.

11 citations

chicken / avianmetabolomics

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedFeb 21, 2024

EPINEST, an agent-based model to simulate epidemic dynamics in large-scale poultry production and distribution networks

Francesco Pinotti, José Lourenço, Sunetra Gupta…·Guillaume Fournié

EPINEST simulates epidemic dynamics in poultry production networks to study pathogen transmission and health hazards.

5 citations

experimental assay

𝕏 PostBluesky