Author
Broad InstituteORCID 0000-0003-2652-5828Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
A.K. Basak, Carolina Ortiz‐Cordero, Stephanie Pei Tung Yiu…·Laura L. Kiessling
The paper introduces two methods to profile functional glycan-lectin interactions in tissues using single-cell and spatial multiomic approaches, revealing stimulus-specific glycan remodeling and spatial glycan programs in immune cells and follicular lymphoma.
Constantine N. Tzouanas, Jessica E.S. Shay, Marc Samuel Sherman…·Alex K. Shalek
The paper shows chronic metabolic stress in liver cells drives developmental programs and functional loss, mirroring tumor states and predicting poor cancer survival.
Tyler E. Miller, Chadi A. El Farran, Charles Couturier…·B. E. Bernstein
The paper identifies four immunomodulatory programs in glioma-associated myeloid cells using scRNA-seq and shows they are driven by microenvironmental cues and therapies, not cell type or mutation status.