Author

Sean M. Cahill

Albert Einstein College of MedicineORCID 0000-0003-2877-0704Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:Xenopus· 1

Frequent Co-Authors

David CowburniD· 2 shared András FiseriD· 1 shared Arpita TawaniiD· 1 shared Benjamin M. LortoniD· 1 shared Christopher Warren· 1 shared David ShechteriD· 1 shared Donald F. HuntiD· 1 shared Humaira IlyasiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

David CowburnORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJun 20, 2024

Characterizing interactions in the nuclear pore complex transporter using novel site-specific deuteration and SANS

Arpita Tawani, Shuo Qian, Samuel E Sparks…·David Cowburn

The paper uses site-specific deuteration and SANS to study the dynamic structure of FG Nups interacting with NTF2, revealing their fully disordered nature and lack of significant inter-aromatic contacts.

1 citation

experimental assay

𝕏 PostBluesky

BiochemistryiSciencePeer-reviewedMar 8, 2024

Glutamylation of Npm2 and Nap1 acidic disordered regions increases DNA charge mimicry to enhance chaperone efficiency

Benjamin M. Lorton, Christopher Warren, Humaira Ilyas…·David Shechter

The paper shows that glutamylation of acidic IDRs in Npm2 and Nap1 enhances their DNA mimicry function, improving histone chaperone efficiency in nucleosome assembly.

14 citations

XenopusChIP-seq

𝕏 PostBluesky