Author
Edmund Su
University of British ColumbiaORCID 0000-0003-3156-176XUnclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 38 mutual co-author links5 papers
Recent·Most cited
- Cancer BiologyCancersPeer-reviewed
Genome-wide CRISPR screen identifies KEAP1 perturbation as a vulnerability of ARID1A-deficient cells
Louis-Alexandre Fournier, Forouh Kalantari, James P. Wells…·Peter C. Stirling
The paper identifies KEAP1 as a genetic dependency in ARID1A-deficient clear cell ovarian carcinoma cells through a genome-wide CRISPR screen, showing KEAP1 perturbation leads to growth inhibition.
- Cancer BiologybioRxivPreprint
Synovial Sarcoma Chromatin Dynamics Reveal a Continuum in SS18:SSX Reprograming
Jakob Hofvander, Alvin Qiu, Kiera Lee…·Martin Hirst
This study examines the epigenomic states of synovial sarcoma using multi-omics analysis, revealing a continuum of epigenomic states and identifying H3K4me3 inhibition as a potential therapeutic strategy.
- Genetic & Genomic MedicineJournal of Virological MethodsPeer-reviewed
Optimization of magnetic bead-based nucleic acid extraction for SARS-CoV-2 testing using readily available reagents
Simon Haile, Aidan M. Nikiforuk, Pawan K. Pandoh…·Martin Hirst
The paper optimizes a magnetic bead-based nucleic acid extraction protocol for SARS-CoV-2 testing to reduce cross-well contamination while maintaining sensitivity.
11 citations - GenomicsPLoS Computational BiologyPeer-reviewed
Epiclomal: probabilistic clustering of sparse single-cell DNA methylation data
Camila P. E. de Souza, Mirela Andronescu, Tehmina Masud…·Sohrab P. Shah
Epiclomal clusters sparse single-cell DNA methylation data and imputes missing values, outperforming non-probabilistic methods and revealing sub-clonal methylation patterns in tumour genomes.
33 citations