Paul W. Sweeney

This study uses graph theory and imaging techniques to analyze vasculogenic mimicry in vitro and in vivo, showing its association with oxygenation heterogeneity and resistance to anti-angiogenic treatment.

This study uses multi-scale photoacoustic imaging to identify biomarkers of radiation therapy response in breast cancer models, showing improved outcomes with denser vasculature and increased oxygen saturation.

This study develops a framework to monitor and analyze the dynamic formation and dissolution of pseudo-vascular networks in vitro using time-resolved microscopy and image analysis, showing melanoma cells form the most stable networks and respond to specific drug treatments.