Rachel Lena Rutishauser

Robust T and B cell activation is associated with rapid clearance of infectious SARS-CoV-2

The paper identifies immune cell activation patterns associated with rapid clearance of infectious SARS-CoV-2 in both unvaccinated and vaccinated individuals.

A mechanistic basis for CD8+ T cell expansion sensitivity as a predictor of HIV post-treatment control

The paper develops a mechanistic model linking CD8+ T cell expansion sensitivity to HIV post-treatment control, showing strong correlations with Ki-67 and TCF-1 levels.

Immune activation during broadly neutralizing antibody-mediated HIV suppression prior to post-intervention control

This study shows that bNAb-mediated HIV suppression is linked to increased immune activation compared to ART suppression, with unique transcriptional patterns in controllers.

Early immune responses anticipate HIV rebound and precede viral control

The paper identifies early immune responses preceding HIV rebound and links them to viral control outcomes in individuals discontinuing antiretroviral treatment.

CD38 expression by neonatal human naïve CD4+ T cells shapes their distinct metabolic state and high tolerogenic potential

This study shows neonatal human naive CD4+ T cells have higher CD38 expression, linking it to glycolytic metabolism and tolerogenic function compared to adult cells.

The effect of circulating neutralizing antibodies on the replication of SARS-CoV-2 variants following post-vaccination infections.

This study examines how pre-existing neutralizing antibodies affect viral shedding in post-vaccination SARS-CoV-2 infections, finding that higher titers reduce viral load and duration but are less effective against Omicron variants.