Ravi K. Patel

This study shows that bNAb-mediated HIV suppression is linked to increased immune activation compared to ART suppression, with unique transcriptional patterns in controllers.

The paper identifies coordinated variation between immune systems and microbiomes in healthy humans, linking it to tonic interferon states.

The paper shows congenital CMV infection leads to oligoclonal expansion of cytotoxic γδ T cells with fetal-like TCR features in neonates.

The paper identifies shared mechanisms of HBsAg seroclearance using a mouse model and longitudinal PBMCs from CHB patients, showing CD4+ T cell activation is essential for clinical cure.

The paper identifies two immunological subtypes of Sjögren's disease using single-cell RNA sequencing, highlighting distinct IFN-I signatures and transitional B cell characteristics.

This study identifies immune subtypes in hospitalized COVID-19 patients linked to clinical outcomes and long COVID risk through longitudinal multi-omics analysis.

The paper identifies gene regulatory programs distinguishing naive CD8+ T cell subsets using RNA-seq and ATAC-seq data, revealing novel regulators and transcriptional networks.

This study identifies immune programs linked to COVID-19 severity and mortality through longitudinal multi-omics analysis of 1,152 hospitalized patients.

This paper introduces CARP, a method combining RNA-seq and PRO-seq to distinguish direct miRNA targets from downstream regulatory changes, showing improved accuracy and reduced false positives.

This study shows that 3' sequence identity is not required for the established function of miR-146a in myeloid cells in vivo.

This study shows that CDK2 kinase activity regulates male germ cell fate by controlling the balance between stem cell renewal and differentiation, with loss of function leading to infertility.