Author

Evangelia Kokalaki

Autolus (United Kingdom)ORCID 0000-0003-4686-6806Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Isaac GannoniD· 2 shared James SillibourneiD· 2 shared Martin A. PulèiD· 2 shared Mathew P. RobsoniD· 2 shared Saket SrivastavaiD· 2 shared Simon ThomasiD· 2 shared Thomas GrothieriD· 2 shared Anna M. Bulek· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Isaac GannonORCID

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2 papers

Recent·Most cited

ImmunologyCancer Immunology ResearchPeer-reviewedJun 23, 2023

Enhancing CAR T cell therapy using Fab-Based Constitutively Heterodimeric Cytokine Receptors

Matteo Righi, Isaac Gannon, Mathew P. Robson…·Martin A. Pulè

This paper introduces a dimerization domain from IgG1 antibodies to create engineered cytokine receptors that mimic natural heterodimerization, enhancing CAR T cell therapy efficacy.

15 citations

humanproteomics

𝕏 PostBluesky

ImmunologyFrontiers in ImmunologyPeer-reviewedJun 2, 2023

Exploration of T-cell immune responses by expression of a dominant-negative SHP1 and SHP2

Julia Taylor, Anna M. Bulek, Isaac Gannon…·Simon Thomas

This study investigates the role of SHP1 and SHP2 in T-cell immunosuppression by expressing truncated variants and shows that dSHP2 can alleviate PD1-mediated suppression in CAR T cells.

9 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky