Daniel D. Von Hoff

This study shows that inhibiting stromal Class I HDACs reduces pancreatic cancer progression by targeting desmoplastic and pro-tumorigenic programs in cancer-associated fibroblasts.

This study characterizes urine cfDNA fragmentation patterns and shows they reflect sub-nucleosomal organization, with potential for cancer diagnostics.

SuperCT improves single-cell transcriptomic analysis by using a supervised classifier to accurately identify cell types from RNA expression profiles, outperforming traditional unsupervised methods.