Cancer BiologyNature CommunicationsPeer-reviewed
Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D
Biswanath Chowdhury, Kaiyuan Zhu, Chaohui Li…·Vineet Bafna
The paper introduces ec3D, a method to reconstruct 3D structures of ecDNA from Hi-C data, revealing spherical configurations and unique long-range interactions in cancer.