Cell BiologyScience China Life SciencesPeer-reviewed
Structural insights into dual-antagonize mechanism of AB928 on adenosine A2 receptors
Yuan Weng, Xinyu Yang, Qiansen Zhang…·Gaojie Song
This study determines the crystal structures of A2AR with AB928 and 2-118, revealing distinct binding modes on A2AR and A2BR that explain AB928's dual-antagonistic properties.