ImmunologybioRxivPreprint
The systemic JIA synovial fluid environment supports development and prevalence of specific inflammatory T helper cell phenotypes
Susanne Schleifenbaum, Aljoscha Swoboda, Johannes Dirks…·Christoph Kessel
This study compares how synovial fluid from systemic juvenile idiopathic arthritis (sJIA) and JIA patients influences T helper cell polarization, showing sJIA SF promotes a specific Tph phenotype linked to IL-1β, IL-18, and GM-CSF.
DOI 10.1101/2025.07.01.661738