Molecular BiologybioRxivPreprint
A Genome-Wide CRISPR Screen Identifies Sortilin as the Receptor Responsible for Galectin-1 Lysosomal Trafficking
Justin Donnelly, Roarke A. Kamber, Simon Wisnovsky…·Carolyn Ruth Bertozzi
The paper identifies sortilin as the receptor mediating galectin-1 lysosomal trafficking through a CRISPR screen and demonstrates its use for siRNA delivery.
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