Cell BiologybioRxivPreprint
Actin-dependent mechanotransduction controls nucleocytoplasmic partitioning of DNMT3a through ERK1/2 signaling during cutaneous wound healing
Johan Ajnabi, Binita Dam, Ekta Gupta…·Colin Jamora
The paper shows that actin remodeling during wound healing inactivates ERK1/2, unmasking DNMT3a's nuclear localization signal and enabling its nuclear translocation to regulate epigenetic reprogramming.
DOI 10.64898/2026.01.15.699481