BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Leveraging co-evolutionary insights and AI-based structural modeling to unravel receptor-peptide ligand-binding mechanisms
Simon Snoeck, Hyun Kyung Lee, Marc W. Schmid…·Cyril Zipfel
The paper identifies SCOOP-MIK2 binding mechanisms using in silico analysis, AlphaFold-Multimer, and experimental validation, revealing conserved binding pockets and their functional importance.
36 citationstop 2%