FUMA: Functional mapping and annotation of genetic associations

A main challenge in genome-wide association studies (GWAS) is to prioritize genetic variants and identify potential causal mechanisms of human diseases. Although multiple bioinformatics resources are available for functional annotation and prioritization, a standard, integrative approach is lacking. We developed FUMA: a web-based platform to facilitate functional annotation of GWAS results, prioritization of genes and interactive visualization of annotated results by incorporating information from multiple state-of-the-art biological databases.