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BioinformaticsThe Annals of Applied Statistics
Peer-reviewed journal article

Bayesian Additive Regression Trees for Genotype by Environment Interaction Models

Danilo Augusto SartiiD, Estevão B. PradoiD, Alan InglisiD, Antônia A. L. dos Santos, Catherine HurleyiD, Rafael de Andrade MoraliD, Andrew C. ParnelliD

Abstract

We propose a new class of models for the estimation of genotype by environment (GxE) interactions in plant-based genetics. Our approach, named AMBARTI, uses semi-parametric Bayesian additive regression trees to accurately capture marginal genotypic and environment effects along with their interaction in a cut Bayesian framework. We demonstrate that our approach is competitive or superior to similar models widely used in the literature via both simulation and a real world dataset. Furthermore, we introduce new types of visualisation to properly assess both the marginal and interactive predictions from the model. An R package that implements our approach is available at https://github.com/ebprado/ambarti.

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02 /Specification & Classification

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