The Scramble Conversion Tool
Abstract
MotivationThe reference CRAM file format implementation is in Java. We present \"Scramble\": a new C implementation of SAM, BAM and CRAM file I/O.\n\nResultsThe C API for CRAM is 1.5-1.7x slower than BAM at decoding, but 1.8-2.6x faster at encoding. We see file size savings of 40-50%.\n\nAvailabilitySource code is available from http://sourceforge.net/projects/staden/files/io_lib/
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