spatial domain detection

This study shows serotonergic psychedelics like LSD and DMT delay resting state neurovascular coupling, affecting hemodynamic delays and functional connectivity in brain regions with serotonin receptors.

Diffusion MRI tractography below 750 µm resolves the dorsal superior longitudinal fasciculus into layered fiber systems of varying length, matching macaque tracing; 1.5 mm tractography misses this.

This study characterizes brain maturation in larval zebrafish using brain-wide imaging, revealing changes in functional connectivity, network organization, and cellular activity patterns.

SPEAR combines laser microdissection and LC-MS/MS to enable spatial epitranscriptomic profiling of FFPE tissue, revealing RNA modification changes in glioma progression.

The paper investigates chromatin state reorganization during leg regeneration in pancrustaceans, finding a conserved sequence of chromatin resetting and pioneer factor activation across species.

The paper identifies brainstem circuits that transform dental sensory input into coordinated jaw opening by linking sensory afferents to specific motor pools.

The paper shows alcohol exposure disrupts chromatin by altering CTCF and cohesin occupancy at guanine-rich sites, leading to lasting gene expression changes.

This paper develops a 2D hydrogel platform to study how mechanical and biochemical cues influence acinar-to-ductal metaplasia in pancreatic cells.

This study shows that KDM4 inhibition changes chromatin structure and transcription in embryonic stem cells, with some effects dependent on Setdb1 status.

The paper examines depth-dependent coupling between neuronal activity and fMRI in the human auditory cortex during naturalistic music listening, revealing spectrolaminar organization of neurovascular coupling.

This study shows maternal obesity accelerates cardiomyocyte maturation in offspring, leading to adult heart dysfunction through cytoarchitectural disruption.

The paper investigates spatial and temporal metabolic and physiological changes in Sansevieria cylindrica leaves under heat, drought, and rewatering conditions, identifying key metabolites that distinguish treatment phases and leaf positions.

The paper shows that theta-phase timing of spikes encodes spatial and image information beyond firing rate in hippocampal neurons.

SMODER deconvolves spatial multi-omics data by prioritizing RNA for cell-type identification and integrating other modalities, improving accuracy and spatial coherence.

The paper analyzes spatial organization of immune and epithelial cells in colorectal and pancreatic cancers using multiplexed imaging, finding differences in conditional coordination and proximity between disease subtypes.

This study shows that home-cage activity monitoring captures non-motor symptoms in EAE, providing an observer-independent measure of disease progression in MS models.

This paper introduces a workflow combining 3D-PLI, immunohistochemistry, and Nissl staining to map fiber architecture and cell types in brain sections with high resolution and reduced inter-subject variability.

The paper links individualized cortical folding topology to diffusion properties in cortical and superficial white matter using diffusion MRI data.

This paper develops a spatial pharmacology workflow using LCM-LC-PRM to profile MMAE distribution in tumour and healthy tissues, revealing heterogeneous and time-dependent accumulation patterns.

The paper uses Bayesian hierarchical spatial models to predict the relative abundance of three tick species in Illinois based on environmental and spatial data.

The paper develops transgenic mouse lines with red fluorescent labeling of myelin, enabling structural and functional imaging compatible with green spectral sensors.

SVC predicts subcellular transcript localization and co-organization using a Vision Transformer model, revealing disease patterns and spatial biology not accessible at the cell level.

This study uses bird-borne sensors to map the three-dimensional temperature structure of Rome's urban atmosphere, revealing vertical and horizontal heat patterns not captured by traditional methods.

The paper maps DNA damage response states in aging mouse brains, revealing opposing neuronal and vascular spatial patterns linked to genome maintenance.

The paper shows that the supramammillary nucleus (SuM) acts as an independently tunable theta oscillator, modulated by the prefrontal cortex to control cortical coupling with the hippocampus.

The paper uses virtual brain modelling to identify network-specific alterations in excitation/inhibition profiles in treatment-resistant schizophrenia and links them to symptom severity.

This study uses continuous psychophysics in VR to show repulsion away from straight ahead in heading perception, supporting the response-range explanation over egocentric reference frame.

The paper develops BrainMapping to align rat and human cortices using resting-state fMRI, revealing distributed and directionally asymmetric correspondences between species.