Topic · Cancer Research · Biochemistry, Genetics and Molecular Biology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
544 papers
Jörn M. Schmiedel, Debora S. Marks, Ben Lehner, Nils Blüthgen
The paper shows microRNAs primarily control expression noise rather than repress protein levels, and this noise control is widespread across species.
Annita Louloupi, Evgenia Ntini, Julia Liz, Ulf Andersson Ørom
The paper develops a method to study pri-miRNA processing kinetics in vivo and shows co- and post-transcriptional processing occurs with varying speeds.
Aristeidis G. Telonis, Rogan G. Magee, Phillipe Loher…·Isidore Rigoutsos
The paper shows that binary isomiR profiles can accurately classify 32 TCGA cancer types with high sensitivity and low false discovery rate.
Bailey C. E. Peck, Amanda T. Mah, Wendy A. Pitman…·Praveen Sethupathy
The paper shows microbiota regulate miRNA expression in intestinal stem cells more than other cell types, with miR-375 suppression linked to increased stem cell proliferation.