Macrophages Promote Aortic Valve Cell Calcification Through STAT3 Splicing
Michael A. Raddatz, Tessa M. Huffstater, Matthew R. Bersi…·W. David Merryman
This study shows that macrophages in Notch1+/- mice promote osteogenic calcification in aortic valves through STAT3 splicing changes and increased recruitment and polarization.