Hearing Loss and Rehabilitation

Establishment of a cochlear lymphatic vascular network and immune surveillance system following cochlear implantation

This study identifies a lymphatic vascular network and immune surveillance system in the cochlea following implantation, contributing to inflammatory responses.

Extended high frequency hearing influences cortical response amplitudes to speech

This study shows that deficits in extended high-frequency hearing reduce cortical response amplitudes to speech, even in young adults, and highlights the need to include EHF hearing in clinical assessments and hearing aid design.

Distinct Roles of Working Memory and Inhibitory Control in Speech-in-Noise Perception

This study examines how working memory and inhibitory control affect speech-in-noise perception across the adult lifespan and finds that both cognitive functions predict performance on different types of speech-in-noise tasks.

Fatigue-related changes in value-based decision-making during listening are associated with increased frontal cortical activation

This study examines how listening fatigue affects value-based decision-making and frontal cortical activation in hearing aid users.

Acoustic Masking of Electric Stimulation at Basal and Extra-Cochlear Sites

This study investigates acoustic masking of electric stimulation at different cochlear sites in EAS users, finding strong masking for apical stimulation correlated with residual hearing.

Effect of Spatial Release from Masking on Listening Effort in Different Semantic Contexts

The paper examines how spatial and semantic cues affect speech intelligibility and listening effort in noisy environments, finding spatial release from masking benefits both coherent and anomalous sentences but with differing impacts on listening effort.

Multichannel optical cochlear implants enable spectrally distinct auditory activity

This paper demonstrates that multichannel optical cochlear implants (oCIs) with ChReef enable improved spectral resolution compared to electrical stimulation in gerbils.

Long-term mitigation of the foreign-body response with dexamethasone-eluting cochlear implants in mice

This study shows dexamethasone-eluting cochlear implants reduce and sustainably suppress the foreign-body response in mice over 336 days, with reduced fibrosis and immune infiltration.

The Effect of Plosive Content on the Loudness Perception of Vowel-Consonant-Vowel Syllables in Listeners with Sensorineural Hearing Loss

This study examines if plosive consonants are perceived as louder than non-plosive consonants by hearing-impaired listeners, finding no overall difference but some individual consonant effects.

In silico framework for benchmarking optogenetic hearing restoration

This paper develops an in silico framework to model optogenetic hearing restoration and finds that improved spectral selectivity compensates for lower temporal fidelity in optogenetic stimulation.

Structural integrity of auditory-linguistic brain networks varies with cognitive status and accounts for speech-in-noise deficits across the adult lifespan

The paper examines how structural changes in auditory-linguistic brain networks relate to cognitive status and speech-in-noise perception in older adults.

Chirped Speech (Cheech) Enables Rapid Assessment of Multi-Level Auditory Evoked Potentials During Speech-in-Noise Recognition

This study evaluates a chirped-speech stimulus (Cheech) to assess auditory evoked potentials during speech-in-noise recognition, showing it preserves intelligibility while enabling robust neural recordings.

Non-Linear Dorsolateral Prefrontal Recruitment During Speech-in-Noise Perception in Aging

This study investigates how dorsolateral prefrontal cortex activity changes with listening demand in young and older adults during speech-in-noise tasks, finding an inverted U-shaped response pattern and age-related differences in activation levels.

Extracochlear Electric Stimulation - Toward Non-Invasive Hearing Restoration

This paper investigates non-invasive extracochlear electrical stimulation (EEAS) using ear canal electrodes, showing it is feasible and perceptually effective across different hearing statuses, with optimal results using contralateral mastoid electrode configurations.

Revisiting Analog Electrical Stimulation with Current Focusing in a Guinea Pig Model of Cochlear Implants.

This study compares analog and pulsatile stimulation in cochlear implants using guinea pigs, finding analog stimulation has lower activation thresholds but different temporal coding properties.

Older adults show overexaggerated and larger noise-related degradation in their neural tracking of speech

This study finds older adults show exaggerated neural speech tracking in quiet and greater noise-related degradation compared to younger adults, supporting the decline-compensation hypothesis.

Within-electrode temporal envelope processing predicts multi-channel speech outcomes across cochlear implant pulse rates

This study examines how cochlear implant pulse rates affect temporal envelope processing and speech perception in deaf individuals, finding that lower pulse rates impair speech recognition while higher rates show mixed effects.

Auditory Working Memory and Sound Segregation Ability Predict Speech-in-Noise in Adult Cochlear Implant Users

This study shows that auditory working memory and sound segregation ability predict speech-in-noise performance in cochlear implant users, even after accounting for peripheral processing abilities.

Comparison of a Novel Real-World Speech in Noise Auditory Attention Task to Standard Clinical Audiological Metrics

The paper evaluates how age, pure tone audiometry, and cognitive ability predict speech perception in noise using a novel auditory attention task.

Stability of phoneme-related potentials across testing sessions and stimulus presentation conditions

This study evaluates the stability of phoneme-related potentials (PRPs) across different testing conditions and finds they remain stable, suggesting their potential as a reliable measure of speech processing.

Linguistic information compensates for age-related decline in attentional filtering

This study shows older adults compensate for age-related attentional filtering deficits by relying more on linguistic information during speech comprehension in multitalker situations.

Multi-talker speech comprehension at different temporal scales in listeners with normal and impaired hearing

This study examines how hearing-impaired and normal-hearing listeners process speech in multi-talker scenarios, revealing disruptions in neural responses at shorter and longer temporal scales.

Optimal hearing aid design through restoration of the neural code

This paper develops a deep learning-based hearing aid that restores neural coding by simulating normal auditory processing in impaired brains, outperforming existing methods in distortion correction and phoneme recognition.

Neurophysiological Sensitivity to Envelope and Pulse Timing Interaural Time Differences in Cochlear Implanted Rats with Different Hearing Experiences

Selonsertib-Eluting Electrode Coating Attenuates Cochlear Injury Pathways

This study develops a selonsertib-eluting polymer coating for cochlear implants, showing it reduces inflammation, fibrosis, and promotes cell survival in cochlear tissue.

Discrimination of spectrally sparse complex-tone triads in cochlear implant listeners

This study investigates how spectral complexity and temporal presentation affect chord discrimination in cochlear implant users, finding that reduced spectral complexity and temporal envelope cues improve performance.

Best Cochlear Locations for Delivering Interaural Timing Cues in Electric Hearing

This study identifies optimal cochlear locations for delivering interaural timing cues in bilateral cochlear implants to improve sound localization.

Spatial auditory change detection in listeners with hearing loss

This study investigates how sensorineural hearing loss affects spatial auditory change detection, finding that hearing loss, age, and spatial location influence detection accuracy and speed.

Attention Decoding at the Cocktail Party: Preserved in Hearing Aid Users, Reduced in Cochlear Implant Users

This study compares cortical speech tracking and attentional modulation between hearing aid users, cochlear implant users, and typical hearing individuals in noisy environments.

Predicting spectro-temporal modulation detection thresholds with a functional auditory model

The paper evaluates a computational auditory model's ability to predict spectro-temporal modulation detection thresholds in young and older listeners, finding it captures overall patterns but underestimates individual variability.