Patrick Ruther

This paper demonstrates that multichannel optical cochlear implants (oCIs) with ChReef enable improved spectral resolution compared to electrical stimulation in gerbils.

This study compares tissue reactivity to stiff silicon and flexible polyimide implants in mice, finding that flexible polyimide reduces lesions and immune response.

This paper introduces ChReef, an improved optogenetic tool with enhanced performance in sensory and cardiac systems, demonstrating its effectiveness in restoring visual and auditory function.

This paper develops a low-weight, wireless optogenetic cochlear implant system for hearing restoration in deafened rats, demonstrating its ability to enable locomotion tasks in response to acoustic stimulation.

The paper shows that stimulating parvalbumin-positive interneurons in specific cortical layers of awake mice can entrain local field potentials at different frequencies depending on the layer.

This paper develops thin optical fibers and integration techniques to enable large-scale neuronal recordings and ultrafast optogenetic inhibition in freely moving animals.

This paper develops a new neural probe with a silicon backbone and thin polyimide wings for long-term stable in vivo recordings in mice.

This paper introduces a multifunctional optrode for optogenetics, enabling simultaneous drug delivery, optical stimulation, and electrophysiological recording in freely moving rats.

The paper investigates how the placement of recording sites on silicon probes affects neural signal quality, finding edge sites provide better signal quality than center sites in acute recordings.

This paper introduces a high-density CMOS scanning probe for neural recording, demonstrating its ability to capture neural activity across multiple brain regions with improved resolution compared to lower density devices.