Vector-borne infectious diseases

The paper identifies multiple piroplasm parasites in the invasive Asian longhorned tick in the US, including undescribed species and potential human pathogens.

The paper identifies Rickettsia species in ticks from Uganda, finding R. africae most common and R. conorii subsp. israelensis newly detected.

This study identifies the primary hosts of the invasive Asian longhorned tick in New Jersey, finding it preferentially feeds on larger mammals and is highly abundant, raising concerns about its role in disease transmission.

The paper investigates the presence of antimicrobial resistance genes in tick-borne bacterial isolates and finds that most lack these genes, except for Francisella tularensis.

The study detects Ixodiphagus hookeri in Ixodes ricinus ticks from Hungary, marking the first report in the country and the southernmost occurrence in Central Europe.

The paper analyzes 289 black-legged tick datasets to show that study design factors like length, sampling technique, life stage, and geographic scope affect the detection of stable population patterns.

The paper uses single-cell RNA sequencing to analyze three Babesia species, identifying conserved and species-specific gene expression patterns across the asexual replication cycle.

This study identifies differentially expressed miRNAs in Ixodes scapularis salivary glands after Borrelia burgdorferi infection using small RNA sequencing and qRT-PCR.

CoxBase provides an online platform for managing, analyzing, and typing Coxiella burnetii genomic sequences to support epidemiological surveillance.

This paper develops a deep learning model to identify tick species from images, achieving 87.8% accuracy but underperforming experts due to image quality issues.

This study investigates the role of two tick enzymes, ADGal and β-1,4GalT, in galactose metabolism and their potential involvement in Alpha-Gal Syndrome.

The paper develops a multiplex PCR method for diagnosing co-infected hemo-parasites in cattle, showing moderate agreement with Giemsa stained blood smears.

The paper predicts type IV effectors in Ehrlichia spp. and related bacteria, identifying conserved and species-specific effectors and new domain combinations.

This study identifies 25 genes associated with Coxiella burnetii infection in Drosophila using GWAS and functional validation.

This paper develops a digital PCR assay for detecting Borrelia burgdorferi DNA in Lyme disease patient blood, achieving higher sensitivity than current methods.

The paper develops a capture-based DNA enrichment method to assemble the first buffalo-derived T. parva genome, revealing high genetic diversity between cattle- and buffalo-associated strains.

The paper compares the genetic diversity of Theileria annulata in cattle and water buffalo in Pakistan, finding higher diversity in cattle-derived populations.

This paper investigates the role of BbRad51 in segmental gene conversion (SGC) and antigenic variation in Babesia bovis, finding that while BbRad51 influences transcriptional switching and SGC tract lengths, it is not essential for SGC itself.

The paper surveys questing ticks in the Maasai Mara National Reserve to identify pathogens, endosymbionts, and blood-meal sources, revealing zoonotic risks and potential disease vectors.

This study molecularly detects pathogens in ticks and fleas from companion dogs and cats in East and Southeast Asia, finding high prevalence of zoonotic vector-borne pathogens.

The paper identifies a subtype of p67 allele type 1 in buffalo-derived T. parva parasites from southern Africa, distinct from East African cattle-derived parasites.

The paper re-annotates the Theileria parva genome, refining 53% of the proteome and uncovering a minimal N-glycosylation pathway.

This study identifies tick saliva proteins injected during feeding using LC-MS/MS, finding 284 conserved proteins that may serve as vaccine targets.

The study screens tick-borne pathogens in ticks from Corsica, finding DNA of 11 previously unreported species in 48% of tick pools.

The paper identifies 10 blood proteins with altered serum levels in early Lyme disease patients, developing a 10-protein panel for potential diagnostic use.

This study shows ticks use radiant heat sensed by their Hallers organ to find hosts and demonstrates repellents disrupt this heat sensing without affecting odor-based host-seeking.

This paper knocks out the Bbrad51 gene in Babesia bovis and shows that an artificial chromosome platform can complement the loss of function, though it may cause recombination with native chromosomes.

The paper analyzes the whole-body transcriptome of Ixodes ricinus ticks to study gene expression changes during feeding and compares genetic variation between wild and lab strains.