Bacterial biofilms and quorum sensing

This study investigates how taxifolin interacts with the LasR transcriptional regulator of Pseudomonas aeruginosa using molecular docking, dynamics simulations, and machine learning to identify two binding modes.

This study investigates how quercetin interacts with LasR, a transcriptional regulator in Pseudomonas aeruginosa, to inhibit quorum sensing and biofilm formation through two distinct binding modes.

The paper investigates how cell-cell communication circuits operate in a heterogeneous environment, finding that signal diffusion and colony placement affect communication range and speed.