Topic · Oncology · Medicine

Viral-associated cancers and disorders

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

Molecular Biology·Journal of VirologyPeer-reviewed·Oct 11, 2018
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The interaction between ORF18 and ORF30 is required for late gene expression in Kaposi’s sarcoma-associated herpesvirus
Angelica F. Castañeda, Britt A. Glaunsinger
This study identifies the critical role of the ORF18-ORF30 interaction in KSHV late gene expression through mutational analysis.
21 citations
experimental assay
·𝕏 Post·Bluesky
Molecular Biology·bioRxivPreprint·Aug 2, 2018
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(-)-Epigallocatechin-3-gallate inhibition of Epstein-Barr virus lytic replication involves latent membrane protein 1-mediated MAPK signaling pathways
Hongde Li, Xiangjian Luo, Jianmin Hu…+8 more authors·Ya Cao
This study shows that LMP1 promotes EBV reactivation via MAPK signaling and that EGCG inhibits this process by suppressing LMP1-mediated signaling.
DOI 10.1101/383497
human·statistical model
·𝕏 Post·Bluesky
Molecular Biology·Journal of VirologyPeer-reviewed·Jun 5, 2018
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Kaposi’s sarcoma-associated herpesvirus ORF68 is a DNA binding protein required for viral genome cleavage and packaging
Matthew R. Gardner, Britt A. Glaunsinger
This study identifies KSHV ORF68 as a DNA-binding protein essential for viral DNA cleavage and packaging, revealing its role in capsid formation and infectious virion production.
24 citations
experimental assay
·𝕏 Post·Bluesky
Genomics·bioRxivPreprint·Apr 10, 2017
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Cataloguing Over-Expressed Genes In Epstein Barr Virus Immortalized Lymphoblastoid Cell Lines Through Consensus Analysis Of PacBio Transcriptomes Corroborates Hypomethylation Of Chromosome 1
Sandeep Chakraborty
3 citations
human·long-read sequencing
·𝕏 Post·Bluesky