Maternal Mental Health During Pregnancy and Postpartum

The paper identifies DNA methylation regions associated with postpartum depressive symptoms and finds overlap with genome-wide association study results for depression.

This study examines how prenatal depression relates to brain structure and behavior in preschool children, finding that altered structural connectivity mediates the effect of maternal depressive symptoms on externalizing behavior in males.

This study finds that maternal stress during pregnancy is associated with increased gray matter volume in specific brain regions and higher psychiatric symptom risk in adolescents.

This study examines brain gene expression changes in mice with STS deficiency and their response to pharmacological treatment, finding limited significant changes but enrichment in olfactory transduction pathways.

This study examines resting-state functional connectivity, cortical GABA, and neuroactive steroids in peripartum depressed women compared to healthy controls, finding altered connectivity and correlations with GABA levels and allopregnanolone.

The paper identifies gene expression signatures in cord blood linked to maternal psychological distress and adverse childhood outcomes, revealing molecular pathways associated with neurodevelopmental disorders.

The paper examines how maternal depression affects child behavior, finding sex-dependent mediation by NR3C1 methylation in a longitudinal study from pregnancy to age 5.

This study examines the combined effects of maternal stress and perinatal fluoxetine exposure on adult female mouse behavior, finding no interaction between the two factors.

This study finds that prenatal maternal anxiety affects brain activity in adolescents during a cognitive control task, specifically modulating prefrontal cortical responses to task manipulations.