Topic · Reproductive Medicine · Medicine

Endometriosis Research and Treatment

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Molecular Biology·bioRxivPreprint·Oct 16, 2026
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Interleukin-4 suppresses TIMP-2 transcription during endometriosis: Allele-specific regulation of the TIMP-2 -418G/C promoter by SP1
Susmita Saha, Supratim Ghosh, Tapasi Roy…+3 more authors·Snehasikta Swarnakar
This study identifies an IL-4-SP1-TIMP-2 regulatory axis that contributes to ECM dysregulation in endometriosis and shows the TIMP-2 -418G/C promoter polymorphism affects cytokine-mediated transcription.
DOI 10.64898/2026.10.15.759364
human·bulk RNA-seq
·𝕏 Post·Bluesky