Optical Imaging and Spectroscopy Techniques

This study uses fNIRS and PLS analysis to show how working memory load affects brain activity and performance, revealing task-specific relationships between hemodynamics and accuracy.

STORM-Net provides a fast, automatic, and hardware-free method for registering fNIRS optodes to the scalp, validated on adults and infants with comparable accuracy to existing methods.

The paper introduces MAGICAL, an optical clearing method for in vivo fluorescence microscopy, enhancing imaging depth and resolution in living brains.

This study shows that fNIRS HbO signals in auditory cortex can be misleading due to blood stealing, and combined fNIRS-EEG analysis is needed for accurate interpretation.

The paper introduces a new method to estimate spatially resolved CMRO2 from pO2 measurements using the Laplace method, balancing noise reduction and bias.

This paper demonstrates that hybrid diffuse optical measurements can detect hemodynamic changes in cerebral ischemia within hours in a porcine model, with BFI as a potential biomarker.

This paper introduces a video-based method to estimate probe positions on the scalp for EEG and fNIRS, showing it is reliable, fast, and suitable for infants.

This paper introduces a motion detection method for HD-DOT that improves spatial similarity to fMRI by using a global variance of temporal derivatives metric and motion censoring.

This paper introduces a compact reflectance confocal microscope for neurosurgery with high spatial resolution and potential for label-free, contactless use.

The paper introduces a wavelet-based adaptive algorithm to improve hemodynamic response estimation in fNIRS by incorporating protocol constraints and Kalman filtering.

The paper improves fNIRS analysis by developing a surface-based meshing pipeline for creating high-quality brain models, showing significant improvements in accuracy over existing methods.

The paper develops NIR-II fluorescence microscopy techniques to image cortical vasculature in non-human primates, enabling high-resolution analysis of brain microvascular networks and blood flow.

This study shows that locomotion increases cerebral oxygenation in mice, and this increase is linked to respiration rate and phase.

This paper demonstrates the use of functional photoacoustic imaging with a near-infrared voltage-sensitive dye to record in vivo neural activity in rats without craniotomy, showing distinguishable responses in seizure models.

This study shows that the timing of hemodynamic initial-dip and response better reflects spiking activity than amplitude in anesthetized monkeys.

This study identifies the initial-dip in neuroimaging signals as primarily driven by a decrease in total-hemoglobin, coupled to localized spiking activity.

This study measures brain-to-brain coupling during verbal communication using fNIRS and finds it correlates with fMRI in speech comprehension areas, suggesting fNIRS as a reliable and portable tool for studying communication.